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Priority date, 29 Sep 1995 .. The human factor VIII is synthesized as a single chain molecule of approximately 300 kDa and consists of the structural domains A1-A2-B-A3-C1-C2 (Gitschier et al, 1984, .. Insbesondere wird die Chromatographie der vorliegenden Erfindung auf einem Q Sepharose TM FF-Gel durchgeführt.

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